⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28094693 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL28120372 | 0.98 | — | — | |
| Trifluoroacetic Acid SCHEMBL29888481 | 0.86 | MAPT (0.40) | — | |
| SCHEMBL30663307 | 0.82 | TPMT (0.57) | — | |
| SCHEMBL8866037 | 0.79 | TRPA1 (0.48) | — | |
| SCHEMBL1380931 | 0.78 | RAB9A (0.41) | — | |
| SCHEMBL142183 | 0.77 | — | — | |
| SCHEMBL1629796 | 0.77 | — | — | |
| Methylamine SCHEMBL27945126 | 0.76 | TRPA1 (0.47) | — | |
| SCHEMBL23493281 | 0.76 | TRPA1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 399 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240051949-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | UNIV LEUVEN KATH (BE) | 2024-02-15 | — | — | US | claimed |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | claimed |
| CN-116694026-A | High-performance self-repairing epoxy resin and preparation method thereof | 中国人民解放军国防科技大学 | 2023-09-05 | — | — | CN | claimed |
| EP-3183232-B1 | SUBSTITUTED 1-ARYLETHYL-4-ACYLAMINOPIPERIDINE DERIVATIVES AS OPIOID/ALPHA-ADRENORECEPTOR MODULATORS AND METHOD OF THEIR PREPARATION | UNIV ARIZONA (US) | 2023-05-03 | — | — | EP | claimed |
| CN-105130970-B | N- sulfonyl homoserine lactone analog derivative, preparation method and use | 中国人民解放军军事医学科学院毒物药物研究所 | 2019-06-25 | — | — | CN | claimed |
| CN-109890826-A | A kind of efficient IDO/TDO double inhibitors containing azacyclo- helical structure | 中国科学院上海有机化学研究所 | 2019-06-14 | — | — | CN | claimed |
| CN-106459030-B | Replace tropane derivatives | 东亚荣养株式会社 | 2019-01-29 | — | — | CN | claimed |
| CN-107531660-A | α cinnamide compounds and composition as HDAC8 inhibitor | 福马治疗股份有限公司 | 2018-01-02 | — | — | CN | claimed |
| EP-1660507-B2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | MILLENNIUM PHARM INC (US) | 2017-01-04 | — | — | EP | claimed |
| CN-106163284-A | 3-substituted carbonyl naphtho [2,3-b ] furan derivative or pharmaceutically acceptable salt thereof | 北京强新生物科技有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-1178652-C | Mizoribine tablet with improved color | 旭化成制药株式会社 | 2004-12-08 | — | — | CN | claimed |
| EP-1441725-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2004-08-04 | — | — | EP | claimed |
| US-20040048868-A1 | Benzimidazoles | AVENTISUB LLC | 2004-03-11 | — | — | US | claimed |
| WO-2003035065-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS | AVENTIS PHARMACEUTICALS INC (US) | 2003-05-01 | — | — | WO | claimed |
| CN-1353609-A | Amide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES CO (US) | 2002-06-12 | — | — | CN | claimed |
| CN-1307867-A | Mizoribine tablet with improved color | ASAHI CHEMICAL IND (JP) | 2001-08-15 | — | — | CN | claimed |
| CN-1177356-A | Bicyclic benzazepine derivatives as vasopressin antagonists | AMERICAN CYANAMID CO (US) | 1998-03-25 | — | — | CN | claimed |
| CN-88100563-A | N-heterocycle-N-(4-piperidyl) acid amides and the constituent of medicine and the application method of this compounds | — | 1988-08-17 | — | — | CN | claimed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| EP-0006012-A1 | Furan-3-carboxanilide-based fungicidal compositions and method of applying them | UNIROYAL LIMITED (GB) | 1979-12-12 | — | — | EP | claimed |