Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | MMP3 | P08254 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959199 | 1.00 | AKR1C3 (0.39) | AKR1C3AKR1C1MMP2MMP9TDP1 | |
| SCHEMBL13479960 | 1.00 | AKR1C3 (0.39) | AKR1C3AKR1C1MMP2MMP9TDP1 | |
| SCHEMBL8319431 | 1.00 | AKR1C3 (0.39) | AKR1C3AKR1C1MMP2MMP9TDP1 | |
| SCHEMBL8320747 | 0.96 | TDP1 (0.41) | MMP2TDP1PSEN1PSEN2APH1B | |
| SCHEMBL2969395 | 0.96 | TDP1 (0.41) | MMP2TDP1PSEN1PSEN2APH1B | |
| SCHEMBL8319435 | 0.90 | MMP2 (0.48) | AKR1C3AKR1C1MMP2MMP9ALDH1A1 | |
| SCHEMBL8319047 | 0.88 | PSEN1 (0.52) | AKR1C3AKR1C1PSEN1PSEN2APH1B | |
| SCHEMBL8327363 | 0.88 | MMP2 (0.48) | AKR1C3AKR1C1MMP2MMP9TDP1 | |
| SCHEMBL16298354 | 0.87 | MMP2 (0.49) | MMP2MMP9MMP8MMP3MMP1 | |
| SCHEMBL13480199 | 0.87 | MMP2 (0.49) | MMP2MMP9MMP8MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060874-A1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | WO | disclosed |