SCHEMBL16298656

SCHEMBL16298656

C=Cc1ccc([Si](C)=O)cc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 1/20 0.40
HDAC8 Q9BY41 2/20 0.39
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TP53 P04637 2/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1783183 0.80 ALDH1A1 (0.58) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL8992220 0.80 ALDH1A1 (0.58) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL8992209 0.74 ALDH1A1 (0.65) ALDH1A1TDP1TSHRHDAC8TP53
SCHEMBL8992490 0.73 ALDH1A1 (0.54) ALDH1A1TDP1TSHRHDAC8TP53
SCHEMBL7639 0.72 ALDH1A1 (1.00) ALDH1A1TDP1TSHRHDAC8TAS1R3
SCHEMBL473081 0.72 ALDH1A1 (1.00) ALDH1A1TDP1TSHRHDAC8TAS1R3
Methyl Alcohol SCHEMBL28639806 0.70 ALDH1A1 (0.79) ALDH1A1TDP1TSHRHDAC8TAS1R3
Hydrochloric Acid SCHEMBL23581954 0.69 ALDH1A1 (0.92) ALDH1A1TDP1TSHRHDAC8TAS1R3
Ethylene SCHEMBL7955374 0.69 ALDH1A1 (0.92) ALDH1A1TDP1TSHRHDAC8TAS1R3
Water SCHEMBL20378930 0.69 ALDH1A1 (0.92) ALDH1A1TDP1TSHRHDAC8TAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-20090081447-A1 OPTICAL FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed