SCHEMBL1783183

SCHEMBL1783183

C=Cc1ccc([Si](C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.34
TRPA1 O75762 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992220 0.84 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL16298656 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL8992209 0.78 ALDH1A1 (0.65) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL8992490 0.77 ALDH1A1 (0.54) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL7639 0.76 ALDH1A1 (1.00) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL473081 0.76 ALDH1A1 (1.00) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL10649685 0.76
Methyl Alcohol SCHEMBL28639806 0.74 ALDH1A1 (0.79) ALDH1A1TSHRHDAC8TDP1TP53
Hydrochloric Acid SCHEMBL23581954 0.73 ALDH1A1 (0.92) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL22496003 0.73 ALDH1A1 (0.92) ALDH1A1TSHRHDAC8TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10029117-B2 Systems and methods for interior energy-activation from an exterior source IMMUNOLIGHT, LLC (US) 2018-07-24 US claimed
US-9630022-B2 Plasmonic assisted systems and methods for interior energy-activation from an exterior source IMMUNOLIGHT, LLC. (US) 2017-04-25 US claimed
US-9278331-B2 Systems and methods for interior energy-activation from an exterior source IMMUNOLIGHT, LLC (US) 2016-03-08 US claimed
US-20150290614-A1 SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE IMMUNOLIGHT, LLC. (US) 2015-10-15 US claimed
US-20150182934-A1 SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE IMMUNOLIGHT, LLC. (US) 2015-07-02 US claimed
US-8927615-B2 Plasmonic assisted systems and methods for interior energy-activation from an exterior source IMMUNOLIGHT, LLC (US) 2015-01-06 US claimed
US-20140163303-A1 PLASMONIC ASSISTED SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE DUKE UNIVERSITY (US) 2014-06-12 US claimed
US-20130240758-A1 PLASMONIC ASSISTED SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE IMMUNOLIGHT, LLC (US) 2013-09-19 US claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
JP-8127657-A None JP disclosed
CN-119978228-A Preparation method of flexible material for violent sorting and high-temperature early warning in fire material evidence transportation 应急管理部沈阳消防研究所 2025-05-13 CN disclosed
CN-119708755-A Self-healing type fire physical evidence logistics transportation buffer material and preparation method thereof 应急管理部沈阳消防研究所 2025-03-28 CN disclosed
EP-2711075-B1 Plasmonic assisted systems and methods for interior energy-activation from an exterior source. IMMUNOLIGHT LLC (US) 2024-05-22 EP disclosed
US-20240042233-A1 TUMOR IMAGING WITH X-RAYS AND OTHER HIGH ENERGY SOURCES USING AS CONTRAST AGENTS PHOTON-EMITTING PHOSPHORS HAVING THERAPEUTIC PROPERTIES IMMUNOLIGHT, LLC (US) 2024-02-08 US disclosed
US-6051625-A Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA, LTD. (JP) 2000-04-18 US disclosed
EP-0816419-A2 Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom DOW CORNING ASIA, Ltd. (JP) 1998-01-07 EP disclosed
JP-H08127657-A PRODUCTION OF CURED DIPHENYLSILOXANE AND CURED PRODUCT DOW CORNING ASIA LTD 1996-05-21 JP disclosed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240042233-A1 TUMOR IMAGING WITH X-RAYS AND OTHER HIGH ENERGY SOURCES USING AS CONTRAST AGENTS PHOTON-EMITTING PHOSPHORS HAVING THERAPEUTIC PROPERTIES P2RY1, PYGL, P2RX1 ALDH1A1 4355/4885TSHR 370/4885HDAC8 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.