SCHEMBL1629894

SCHEMBL1629894

C=CC(=O)OCCc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 6/20 0.47
TSHR P16473 5/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 3/20 0.42
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
MET P08581 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
CYP3A4 P08684 1/20 0.39
AKR1B10 O60218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915816 1.00 THRB (0.47) THRBTSHRHPGDALDH1A1TP53
SCHEMBL14408226 1.00 THRB (0.47) THRBTSHRHPGDALDH1A1TP53
SCHEMBL13153783 0.99 THRB (0.46) THRBTSHRHPGDALDH1A1TP53
SCHEMBL20733416 0.96 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL26531992 0.96 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2309026 0.96 THRB (0.43) THRBTSHRHPGDALDH1A1TP53
SCHEMBL2609795 0.94 MET (0.48) THRBTSHRHPGDALDH1A1TP53
SCHEMBL13840004 0.94 THRB (0.58) THRBTSHRHPGDALDH1A1TP53
SCHEMBL12234233 0.94 THRB (0.42) THRBTSHRHPGDALDH1A1TP53
SCHEMBL11987130 0.93 THRB (0.49) THRBTSHRHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 257 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024122272-A1 IMAGE FORMING DEVICE AND PROCESS CARTRIDGE キヤノン株式会社 2024-06-13 WO disclosed
WO-2024122192-A1 IMAGE FORMING DEVICE AND PROCESS CARTRIDGE キヤノン株式会社 2024-06-13 WO disclosed
US-11782353-B2 Method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
US-11782353-B2 Method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
US-11754901-B2 Electrochromic device, wearable device, and method for driving electrochromic device RICOH COMPANY, LTD. (JP) 2023-09-12 US disclosed
EP-4170431-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2023-04-26 EP disclosed
US-20230124743-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-04-20 US disclosed
US-11319484-B2 Electrochromic element and method for manufacturing electrochromic element RICOH COMPANY, LTD. (JP) 2022-05-03 US disclosed
US-11237447-B2 Electrochromic element RICOH COMPANY, LTD. (JP) 2022-02-01 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
EP-0740216-A2 Polymer, electrophotographic photosensitive member and electroluminescence device using the polymer, process cartridge and electrophotographic apparatus using the electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 1996-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319484-B2 Electrochromic element and method for manufacturing electrochromic element TET2, ESR1, ESYT2 THRB 3974/4885TSHR 2715/4885HPGD 2190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.