SCHEMBL1629917

SCHEMBL1629917

[C-]#[N+]c1ccc(C=Cc2ccc(C=Cc3ccccc3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
CHAT P28329 3/20 0.44
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HPGD P15428 1/20 0.41
CASP3 P42574 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
NFE2L2 Q16236 3/20 0.41
TRPA1 O75762 2/20 0.41
MAOB P27338 2/20 0.41
CYP19A1 P11511 1/20 0.41
MAOA P21397 1/20 0.41
APP P05067 1/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1628770 0.95 NFE2L2 (0.44) KDM4ECHATNFE2L2TRPA1MAOB
SCHEMBL1629989 0.86 NFE2L2 (0.50) CHATMEN1KMT2ANFE2L2TRPA1
SCHEMBL1629883 0.86 MAOB (0.52) CHATMEN1KMT2ANFE2L2TRPA1
SCHEMBL1629916 0.86 MAOB (0.52) CHATMEN1KMT2ANFE2L2TRPA1
SCHEMBL11215153 0.84 CHAT (0.55) KDM4ECHATLMNAMAPTMEN1
SCHEMBL11259417 0.84 CHAT (0.55) KDM4ECHATLMNAMAPTMEN1
SCHEMBL1628768 0.83 NFE2L2 (0.42) CHATMEN1KMT2ANFE2L2TRPA1
SCHEMBL1628449 0.82 CHAT (0.57) CHAT
SCHEMBL1629888 0.82 NFE2L2 (0.45) KDM4ECHATNFE2L2TRPA1MAOB
SCHEMBL2502624 0.78 CHAT (0.50) KDM4ECHATLMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835084-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2014-09-16 US disclosed
US-20120087695-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-04-12 US disclosed