Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215153 | 1.00 | CHAT (0.55) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL2502627 | 0.93 | CHAT (0.50) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL2502624 | 0.93 | CHAT (0.50) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL7118094 | 0.92 | NFE2L2 (0.58) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL11544222 | 0.92 | NFE2L2 (0.58) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL7542712 | 0.89 | KDM4E (0.47) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL9971902 | 0.87 | MAOB (0.48) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL14422439 | 0.85 | LMNA (0.57) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL1629917 | 0.84 | KDM4E (0.44) | CHATKDM4ENFE2L2TRPA1MAOB | |
| SCHEMBL1782982 | 0.81 | CHAT (0.68) | CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335055-A | Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |