Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16329971 | 0.99 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045424 | 0.96 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16350635 | 0.93 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL10085174 | 0.93 | FOLH1 (0.48) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16329973 | 0.93 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL12387469 | 0.89 | FOLH1 (0.45) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045429 | 0.88 | TDP1 (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16299298 | 0.88 | TDP1 (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13045386 | 0.87 | FOLH1 (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL16329968 | 0.86 | TDP1 (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027677-A1 | Prion-specific peptoid reagents | NOVARTIS AG | 2012-02-02 | — | — | US | disclosed |
| US-20070087972-A1 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070087972-A1 | Prion-specific peptoid reagents | PRNP, PARL, PCNP | FOLH1 416/4885PLG 912/4885PRSS1 290/4885 |
| US-20120027677-A1 | Prion-specific peptoid reagents | PRNP, PARL, PCNP | FOLH1 416/4885PLG 912/4885PRSS1 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.