Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 13/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232272 | 0.91 | MEN1 (0.40) | P2RX7ALDH1A1TNIKMEN1KMT2A | |
| SCHEMBL10233464 | 0.91 | MEN1 (0.36) | P2RX7ALDH1A1TNIKMEN1KMT2A | |
| SCHEMBL10232607 | 0.91 | AKR1B1 (0.37) | P2RX7TNIK | |
| SCHEMBL2732419 | 0.88 | PDPK1 (0.39) | EGLN1P2RX7MEN1KMT2A | |
| SCHEMBL10233800 | 0.84 | PDPK1 (0.37) | EGLN1POLBP2RX7MEN1KMT2A | |
| SCHEMBL2734482 | 0.83 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL1335829 | 0.81 | MEN1 (0.37) | P2RX7ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL4481402 | 0.80 | MEN1 (0.48) | POLBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL4502946 | 0.79 | AKR1B1 (0.43) | EGLN1POLBALDH1A1HTTMEN1 | |
| SCHEMBL1336725 | 0.77 | MEN1 (0.41) | P2RX7ALDH1A1TNIKMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058173-A1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |