Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232607 | 0.85 | AKR1B1 (0.37) | P2RX7 | |
| SCHEMBL10233464 | 0.85 | MEN1 (0.36) | P2RX7 | |
| SCHEMBL10232272 | 0.84 | MEN1 (0.40) | P2RX7 | |
| SCHEMBL16299986 | 0.83 | EGLN1 (0.40) | P2RX7 | |
| SCHEMBL1335829 | 0.78 | MEN1 (0.37) | P2RX7 | |
| SCHEMBL2732419 | 0.78 | PDPK1 (0.39) | P2RX7 | |
| SCHEMBL10233800 | 0.75 | PDPK1 (0.37) | P2RX7 | |
| SCHEMBL4502946 | 0.74 | AKR1B1 (0.43) | WDR5 | |
| SCHEMBL4481402 | 0.74 | MEN1 (0.48) | — | |
| SCHEMBL4483474 | 0.73 | LMNA (0.45) | WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632454-A1 | HIV INTEGRASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058173-A1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |