Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.69 |
| ▸ | BCL2 | P10415 | 19/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300049 | 0.92 | BAD (0.67) | BCL2L1BCL2 | |
| SCHEMBL554592 | 0.91 | BCL2L1 (0.84) | BCL2L1BCL2 | |
| SCHEMBL554591 | 0.91 | BCL2L1 (0.84) | BCL2L1BCL2 | |
| SCHEMBL554593 | 0.91 | BCL2L1 (0.84) | BCL2L1BCL2 | |
| SCHEMBL553949 | 0.90 | BCL2L1 (0.81) | BCL2L1BCL2 | |
| SCHEMBL553948 | 0.90 | BCL2L1 (0.81) | BCL2L1BCL2 | |
| SCHEMBL553947 | 0.90 | BCL2L1 (0.81) | BCL2L1BCL2 | |
| SCHEMBL12505263 | 0.86 | BCL2L1 (0.75) | BCL2L1BCL2 | |
| SCHEMBL553550 | 0.84 | BCL2L1 (0.86) | BCL2L1BCL2 | |
| SCHEMBL553551 | 0.84 | BCL2L1 (0.86) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |