Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.35 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.35 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | JAK2 | O60674 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16300070 | 0.81 | NPY5R (0.35) | PARGBRD4NPY5RIDH2 | |
| SCHEMBL8987140 | 0.81 | YTHDF2 (0.52) | YTHDF3YTHDF1YTHDF2PDE2ACDC7 | |
| SCHEMBL9522290 | 0.81 | YTHDF2 (0.52) | YTHDF3YTHDF1YTHDF2PDE2ACDC7 | |
| SCHEMBL8552097 | 0.78 | GAA (0.36) | NPY5RIDH2 | |
| SCHEMBL90870 | 0.78 | DRD4 (0.48) | — | |
| SCHEMBL90833 | 0.73 | PIM1 (0.39) | BRD4NPY5RBRD2BRD3 | |
| SCHEMBL2884125 | 0.73 | HTR2B (0.47) | PDE2ABRD4NPY5R | |
| SCHEMBL2884131 | 0.73 | NPY5R (0.49) | NPY5R | |
| SCHEMBL2884128 | 0.73 | HTR2B (0.47) | PDE2ABRD4NPY5R | |
| SCHEMBL8554397 | 0.71 | DAO (0.36) | PARGNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299066-B2 | Compounds having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20120130070-A1 | COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2012-05-24 | — | — | US | disclosed |
| US-8129372-B2 | Compounds having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20110028468-A1 | COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | Shinonogi & Co., Ltd (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130070-A1 | COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | NPY5R, NPY1R, NPY2R | YTHDF3 1549/4885YTHDF1 1513/4885YTHDF2 1489/4885 |
| US-20110028468-A1 | COMPOUNDS HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY | NPY5R, NPY1R, NPY2R | YTHDF3 1549/4885YTHDF1 1513/4885YTHDF2 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.