Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.52 |
| ▸ | YTHDF3 | Q7Z739 | 1/20 | 0.52 |
| ▸ | YTHDF1 | Q9BYJ9 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522290 | 1.00 | YTHDF2 (0.52) | YTHDF2YTHDF3YTHDF1NOTUMHTT | |
| SCHEMBL16300069 | 0.81 | YTHDF3 (0.35) | YTHDF2YTHDF3YTHDF1PDE2ACDC7 | |
| SCHEMBL1348693 | 0.79 | YTHDF3 (0.45) | YTHDF2YTHDF3YTHDF1HPGDPDE2A | |
| SCHEMBL6756097 | 0.71 | TAS2R38 (0.60) | NOTUMHTTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL19583295 | 0.69 | YTHDF2 (0.59) | YTHDF2YTHDF3YTHDF1HPGDSMN1; SMN2 | |
| SCHEMBL29316666 | 0.69 | YTHDF2 (0.59) | YTHDF2YTHDF3YTHDF1HPGDSMN1; SMN2 | |
| SCHEMBL28197130 | 0.69 | YTHDF2 (0.59) | YTHDF2YTHDF3YTHDF1HPGDSMN1; SMN2 | |
| SCHEMBL11374087 | 0.69 | HTT (0.50) | NOTUMHTTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL2331587 | 0.69 | TNKS2 (0.51) | NOTUMHTTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL16382638 | 0.69 | HTT (0.50) | NOTUMHTTHPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |