SCHEMBL1630007

SCHEMBL1630007

O=P(O)(O)C(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PGK1 P00558 2/20 0.33
PGK2 P07205 2/20 0.33
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
MMP2 P08253 1/20 0.32
ACP3 P15309 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491576 0.77 KDM4E (0.41) KDM4ETSHRTDP1PGK1PGK2
SCHEMBL15641961 0.74 KDM4E (0.36) KDM4ETSHRTDP1
SCHEMBL15413307 0.71 KDM4E (0.38) KDM4ETSHRTDP1
SCHEMBL5572612 0.69 KDM4E (0.37) KDM4ETSHRTDP1
SCHEMBL21049195 0.69 KDM4E (0.37) KDM4ETSHRTDP1
SCHEMBL29241367 0.67 KDM4E (0.39) KDM4ETSHRTDP1PGK1PGK2
SCHEMBL776761 0.65 KDM4E (0.33) KDM4ETSHRTDP1
SCHEMBL28709498 0.65 KDM4E (0.46) KDM4ETSHRTDP1PGK1PGK2
SCHEMBL20261810 0.63 KDM4E (0.40) KDM4ETSHRTDP1PGK1PGK2
SCHEMBL2991838 0.63 TDP1 (0.35) KDM4ETSHRTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301537-B2 Methods for recovering hydrocarbon materials from subterranean formations ACULON INC. (US) 2019-05-28 US disclosed
US-20180194993-A1 Methods For Recovering Hydrocarbon Materials From Subterranean Formations ACULON INC. 2018-07-12 US disclosed
US-20170253793-A1 Methods For Recovering Hydrocarbon Materials From Subterranean Formations ACULON INC. 2017-09-07 US disclosed
US-20150252656-A1 Methods For Recovering Hydrocarbon Materials From Subterranean Formations ACULON, INC. (US) 2015-09-10 US disclosed
US-8337985-B2 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. (US) 2012-12-25 US disclosed
US-20110091729-A1 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. (US) 2011-04-21 US disclosed
US-7901777-B2 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. (US) 2011-03-08 US disclosed
US-20100209711-A1 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. 2010-08-19 US disclosed
US-7740940-B2 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. (US) 2010-06-22 US disclosed
EP-2094400-A2 COATED SUBSTRATES, ORGANOMETALLIC FILMS AND METHODS FOR APPLYING ORGANOMETALLIC FILMS TO SUBSTRATES Aculon, Inc. (US) 2009-09-02 EP disclosed
US-20080152930-A1 Coated substrates, organometallic films and methods for applying organometallic films to substrates ACULON, INC. 2008-06-26 US disclosed
WO-2008060582-A2 COATED SUBSTRATES, ORGANOMETALLIC FILMS AND METHODS FOR APPLYING ORGANOMETALLIC FILMS TO SUBSTRATES ACULON, INC. (US) 2008-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110091729-A1 Coated substrates, organometallic films and methods for applying organometallic films to substrates SOD1, AS3MT, SOD3 KDM4E 2177/4885TSHR 4396/4885TDP1 2205/4885
US-20100209711-A1 Coated substrates, organometallic films and methods for applying organometallic films to substrates SOD1, AS3MT, SOD3 KDM4E 2177/4885TSHR 4396/4885TDP1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.