Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.64 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240822 | 0.94 | KDM4E (0.74) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL9468432 | 0.92 | KDM4E (0.68) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| Hydrochloric Acid SCHEMBL2022863 | 0.92 | KDM4E (0.72) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| Hydrogen Sulfide SCHEMBL29062416 | 0.92 | KDM4E (0.72) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL27952524 | 0.92 | KDM4E (0.72) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL4217510 | 0.89 | KDM4E (0.68) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL5462008 | 0.87 | KDM4E (0.77) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL3468140 | 0.85 | SRD5A2 (0.68) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| Trifluoroacetic Acid SCHEMBL7562496 | 0.84 | KDM4E (0.62) | KDM4EPOLBHTTPTGS1AKR1C3 | |
| SCHEMBL17112348 | 0.84 | FFAR1 (0.71) | KDM4EPOLBHTTPTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110137081-A1 | Continuous Method For Producing Amides Of Low Aliphatic Carboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-06-09 | — | — | US | disclosed |
| US-20110089021-A1 | Method For Producing Amides In The Presence Of Superheated Water | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-21 | — | — | US | disclosed |