SCHEMBL17112348

SCHEMBL17112348

COc1ccc(COc2ccc(CC(=O)O)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.71
POLB P06746 2/20 0.71
NPC1 O15118 1/20 0.71
RAB9A P51151 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
KDM4E B2RXH2 1/20 0.62
PLA2G4B P0C869 1/20 0.61
HTT P42858 2/20 0.60
ALDH1A1 P00352 1/20 0.60
MAPT P10636 1/20 0.60
APP P05067 3/20 0.59
PTGS1 P23219 1/20 0.58
AKR1C3 P42330 1/20 0.58
AKR1C2 P52895 1/20 0.58
MAOB P27338 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240822 0.89 KDM4E (0.74) FFAR1POLBNPC1RAB9ASMN1; SMN2
SCHEMBL27952524 0.87 KDM4E (0.72) FFAR1POLBNPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL2022863 0.87 KDM4E (0.72) FFAR1POLBNPC1RAB9ASMN1; SMN2
Hydrogen Sulfide SCHEMBL29062416 0.87 KDM4E (0.72) FFAR1POLBNPC1RAB9ASMN1; SMN2
SCHEMBL1066614 0.86 FFAR1 (0.70) FFAR1PTGS1MAOB
SCHEMBL19926288 0.85 ALDH1A1 (0.65) FFAR1POLBNPC1RAB9ASMN1; SMN2
SCHEMBL4760103 0.85 MAOB (0.67) FFAR1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL4222632 0.84 FFAR1 (0.68) FFAR1PTGS1MAOB
Ammonia Solution, Strong SCHEMBL27788257 0.84 FFAR1 (0.68) FFAR1PTGS1MAOB
Hydrochloric Acid SCHEMBL10622121 0.84 FFAR1 (0.68) FFAR1PTGS1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12303510-B2 Inhibitory effect of low molecular weight compound on cancer and fibrosis NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) 2025-05-20 US disclosed
CN-119613363-A Synthesis method of 4- (2-H-pyranoxy) phenylmalonic acid-4-methoxybenzyl monoester 山西新天源药业有限公司 2025-03-14 CN disclosed
US-11213527-B2 Inhibitory effect of low molecular weight compound on cancer and fibrosis NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) 2022-01-04 US disclosed
US-20210386747-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS KANONCURE, INC. (JP) 2021-12-16 US disclosed
CN-108026104-B Cancer and fibrosis inhibition and regeneration promotion effects using low-molecular-weight compound 国立大学法人鸟取大学 2021-06-18 CN disclosed
EP-3366687-B1 SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS NAT UNIV CORP TOTTORI UNIV (JP) 2020-04-29 EP disclosed
CN-106132417-B Cancer and fibrosis inhibiting effects of low molecular weight compound 国立大学法人鸟取大学 2020-04-14 CN disclosed
US-10597398-B2 Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) 2020-03-24 US disclosed
US-20190055249-A1 SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) 2019-02-21 US disclosed
EP-3366687-A1 SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS National University Corporation Tottori University (JP) 2018-08-29 EP disclosed
US-20180028536-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS KANONCURE, INC. (JP) 2018-02-01 US disclosed
EP-3150207-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS National University Corporation Tottori University (JP) 2017-04-05 EP disclosed
WO-2017047762-A1 SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS 国立大学法人鳥取大学 2017-03-23 WO disclosed
CN-106132417-A Cancer and fibrosis inhibiting effects of low molecular weight compound 国立大学法人鸟取大学 2016-11-16 CN disclosed
WO-2015147107-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS 国立大学法人鳥取大学 2015-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10597398-B2 Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis HDGF, SHC1, HGF FFAR1 2851/4885POLB 3068/4885NPC1 3085/4885
US-12303510-B2 Inhibitory effect of low molecular weight compound on cancer and fibrosis MMP1, SERPINB1, LGALS1 FFAR1 3361/4885POLB 4113/4885NPC1 1707/4885
US-20190055249-A1 SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS HDGF, SHC1, HGF FFAR1 2851/4885POLB 3068/4885NPC1 3085/4885
US-11213527-B2 Inhibitory effect of low molecular weight compound on cancer and fibrosis MMP1, SERPINB1, LGALS1 FFAR1 3361/4885POLB 4113/4885NPC1 1707/4885
US-20210386747-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS MMP1, SERPINB1, LGALS1 FFAR1 3361/4885POLB 4113/4885NPC1 1707/4885
US-20180028536-A1 INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS MMP1, SERPINB1, LGALS1 FFAR1 3361/4885POLB 4113/4885NPC1 1707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.