SCHEMBL240822

SCHEMBL240822

COc1ccc(CC(=O)O)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.74
POLB P06746 1/20 0.74
PTGS1 P23219 1/20 0.70
AKR1C3 P42330 1/20 0.70
AKR1C2 P52895 1/20 0.70
HTT P42858 1/20 0.66
CTBP2 P56545 1/20 0.62
LDHA P00338 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
USP2 O75604 1/20 0.59
TP53 P04637 1/20 0.59
NPC1 O15118 1/20 0.57
PKM P14618 1/20 0.57
CA2 P00918 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
ALDH1A1 P00352 3/20 0.55
GAA P10253 2/20 0.55
HSD17B10 Q99714 1/20 0.55
TSHR P16473 1/20 0.55
NFKB1 P19838 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27952524 0.98 KDM4E (0.72) KDM4EPOLBPTGS1AKR1C3AKR1C2
Hydrochloric Acid SCHEMBL2022863 0.98 KDM4E (0.72) KDM4EPOLBPTGS1AKR1C3AKR1C2
Hydrogen Sulfide SCHEMBL29062416 0.98 KDM4E (0.72) KDM4EPOLBPTGS1AKR1C3AKR1C2
Dimethylamine SCHEMBL1630099 0.94 KDM4E (0.73) KDM4EPOLBPTGS1AKR1C3AKR1C2
SCHEMBL4217510 0.94 KDM4E (0.68) KDM4EPOLBPTGS1AKR1C3AKR1C2
SCHEMBL9468432 0.94 KDM4E (0.68) KDM4EPOLBPTGS1AKR1C3AKR1C2
SCHEMBL3468140 0.91 SRD5A2 (0.68) KDM4EPOLBPTGS1AKR1C3AKR1C2
SCHEMBL6932432 0.89 KDM4E (0.62) KDM4EPOLBPTGS1AKR1C3AKR1C2
Trifluoroacetic Acid SCHEMBL7562496 0.89 KDM4E (0.62) KDM4EPOLBPTGS1AKR1C3AKR1C2
SCHEMBL17112348 0.89 FFAR1 (0.71) KDM4EPOLBPTGS1AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5348 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122051772-A Femtosecond pulse sequence customization system and method based on programmable control 云南祺晶昕光半导体设备有限公司 2026-05-15 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
EP-4690392-A1 MULTI-LASER COMB SOURCE WITH OPTICAL REFERENCING SCHEME FOR MUTUALLY STABILIZING LASER COMBS TO INTERNAL OPTICAL REFERENCE IPG Photonics Corporation (US) 2026-02-11 EP claimed
WO-2025264604-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2025-12-26 WO claimed
US-20250381110-A1 SKIN CARE COMPOSITION AND METHOD OF USING THE SAME PROCTER & GAMBLE (US) 2025-12-18 US claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-20250372935-A1 DISTRIBUTED FILTERS FOR SUPPRESSION OF PARASITIC PROCESSES IN FIBER LASER SYSTEMS NLIGHT INC (US) 2025-12-04 US claimed
WO-2025243208-A2 PROCESS FOR THE PREPARATION AND/OR PURIFICATION OF POLYETHYLENE GLYCOL AND ITS DERIVATIVES, OBTAINED PRODUCT AND USES THEREOF HOVIONE - FARMACIÊNCIA, SA (PT) 2025-11-27 WO claimed
WO-2025228901-A2 BIOCATALYTIC PROCESS FOR THE PRODUCTION OF AROMA CHEMICALS BASF SE (DE) 2025-11-06 WO claimed
EP-4440845-B1 METHOD FOR SURFACE CONTRAST LASER MARKING OF ANODISED ALUMINIUM OR ALUMINIUM ALLOY PARTS SAFRAN AEROSYSTEMS (FR) 2025-10-08 EP claimed
EP-0341935-A2 A solid phase process for synthesizing Thymosin alpha 1 ALPHA-1 BIOMEDICALS, INC. (US) 1989-11-15 EP claimed
US-4839352-A ANTIBIOTICS MERCK & CO., INC. (US) 1989-06-13 US claimed
EP-0288788-A2 Preparation of linear polycarbonates from cyclic oligomer compositions using benzyl carbanion-generating catalyst GENERAL ELECTRIC COMPANY (US) 1988-11-02 EP claimed
US-4778875-A PHENYLACETIC ACID OR SALTS THEREOF GENERAL ELECTRIC COMPANY (US) 1988-10-18 US claimed
EP-0125049-B1 METHOD OF INHIBITING SWEETNESS TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1986-07-30 EP claimed
US-4515970-A Process for preparation of alkanoic acids SOCIETE FRANCAISE HOECHST (FR) 1985-05-07 US claimed
US-4496762-A Process for the preparation of N-(2-(cyclo-hexen-1-yl)ethyl)-4-methoxybenzeneacetamide EASTMAN KODAK COMPANY (US) 1985-01-29 US claimed
EP-0125049-A1 Method of inhibiting sweetness TATE & LYLE PUBLIC LIMITED COMPANY (GB) 1984-11-14 EP claimed
EP-0027891-B1 AMMONIUM SALTS, A PROCESS FOR THE PREPARATION OF AMINES UNDERLYING THESE, AND COATING COMPOSITIONS ON THE BASIS OF MANUFACTURED POLYURETHANE OR EPOXY RESIN PRODUCTS WHICH CONTAIN THE AMMONIUM SALTS BAYER AG (DE) 1983-03-09 EP claimed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US claimed