Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798285 | 0.82 | TSHR (0.57) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL1460210 | 0.81 | ALDH1A1 (0.54) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL1439135 | 0.79 | MAPT (0.53) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL15557828 | 0.77 | STAT3 (0.47) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL399841 | 0.77 | CA12 (0.56) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL177140 | 0.76 | TSHR (0.65) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL320780 | 0.76 | MAPT (0.55) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL12373225 | 0.76 | KDM4E (0.52) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL6139728 | 0.75 | MAPT (0.64) | MAPTKMT2AMEN1LMNAHPGD | |
| SCHEMBL29996684 | 0.75 | MAPT (0.64) | MAPTKMT2AMEN1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479171-A1 | CHROMENE COMPOUND | Tokuyama Corporation (JP) | 2012-07-25 | — | — | EP | disclosed |