Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 6/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | STK10 | O94804 | 1/20 | 0.30 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868678 | 0.90 | FYN (0.40) | PDK2FYNALDH1A1KDM4EMAPT | |
| SCHEMBL10293036 | 0.90 | FYN (0.40) | PDK2FYNALDH1A1KDM4EMAPT | |
| SCHEMBL10267953 | 0.89 | PDK2 (0.35) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL10262943 | 0.88 | PDK2 (0.39) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL10293147 | 0.86 | PRKDC (0.37) | FYNALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL10262267 | 0.86 | CFTR (0.34) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL10262013 | 0.86 | CFTR (0.33) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL10267942 | 0.86 | PDK2 (0.37) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL10262978 | 0.86 | PDK2 (0.37) | CFTRPDK2FYNALDH1A1KDM4E | |
| SCHEMBL15449572 | 0.86 | PDK2 (0.37) | CFTRPDK2FYNALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691120-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | CFTR 4756/4885PDK2 334/4885FYN 3118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.