SCHEMBL163027

SCHEMBL163027

COC(=O)C12CC3CC(C1)CC(C(=O)OC)(C3)C2

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.53
GLA P06280 1/20 0.48
THRB P10828 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163910 0.92 ALDH1A1 (0.51) NPSR1GLATHRBSMN1; SMN2LMNA
SCHEMBL5859999 0.92 NPSR1 (0.47) NPSR1GLATHRBSMN1; SMN2LMNA
SCHEMBL5859987 0.92 NPSR1 (0.47) NPSR1GLATHRBSMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL5859992 0.91 ALDH1A1 (0.50) NPSR1GLATHRBSMN1; SMN2LMNA
SCHEMBL12104073 0.90 NPSR1 (0.45) NPSR1GLATHRBSMN1; SMN2LMNA
SCHEMBL5608439 0.88 ALDH1A1 (0.56) NPSR1GLASMN1; SMN2LMNAALDH1A1
SCHEMBL1578928 0.88 POLB (0.46) NPSR1GLATHRBALDH1A1TSHR
SCHEMBL4524325 0.88 LMNA (0.49) NPSR1GLATHRBLMNAMEN1
SCHEMBL1089145 0.88 TSHR (0.47) NPSR1GLATHRBMEN1KMT2A
SCHEMBL5608918 0.88 NPSR1 (0.51) NPSR1GLATHRBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250066288-A1 DIHYDRAZIDE-DIHYDRAZONE COMPOUNDS WITH ADAMANTYL MOIETY AND A PROCESS FOR SYNTHESIS OF THE SAME PAWAR RUPA SACHIN (IN) 2025-02-27 US claimed
CN-118666689-A Preparation method of 1, 3-adamantane diamine 浙江荣耀生物科技股份有限公司 2024-09-20 CN claimed
WO-2023237924-A1 DIHYDRAZIDE-DIHYDRAZONE COMPOUNDS WITH ADAMANTYL MOIETY AND A PROCESS FOR SYNTHESIS OF THE SAME PAWAR RUPA SACHIN (IN) 2023-12-14 WO claimed
CN-117210976-A High-whiteness viscose fiber spinning oil and preparation method thereof 乌鲁木齐市华泰隆化学助剂有限公司 2023-12-12 CN claimed
US-20250277204-A1 INSECT-DERIVED ASPARTATE DECARBOXYLASES AND VARIANTS THEREOF FOR IMPROVED BETA-ALANINE PRODUCTION MOJIA BIOTECH LTD. (CN) 2025-09-04 US disclosed
US-20250066288-A1 DIHYDRAZIDE-DIHYDRAZONE COMPOUNDS WITH ADAMANTYL MOIETY AND A PROCESS FOR SYNTHESIS OF THE SAME PAWAR RUPA SACHIN (IN) 2025-02-27 US disclosed
CN-118666689-A Preparation method of 1, 3-adamantane diamine 浙江荣耀生物科技股份有限公司 2024-09-20 CN disclosed
CN-118530979-A Insect-derived aspartate decarboxylase and variants thereof for improving beta-alanine production 广安摩珈生物科技有限公司 2024-08-23 CN disclosed
CN-115261364-B Insect-derived aspartate decarboxylase and variants thereof for improving beta-alanine production 广安摩珈生物科技有限公司 2024-05-31 CN disclosed
EP-4303277-A1 ANTIFOULING COATING COMPOSITION Nitto Kasei Co., Ltd. (JP) 2024-01-10 EP disclosed
EP-4301851-A1 INSECT-DERIVED ASPARTATE DECARBOXYLASES AND VARIANTS THEREOF FOR IMPROVED BETA-ALANINE PRODUCTION Mojia Biotech Ltd. (CN) 2024-01-10 EP disclosed
WO-2023237924-A1 DIHYDRAZIDE-DIHYDRAZONE COMPOUNDS WITH ADAMANTYL MOIETY AND A PROCESS FOR SYNTHESIS OF THE SAME PAWAR RUPA SACHIN (IN) 2023-12-14 WO disclosed
EP-1574495-A1 Adamantane derivatives Daicel Chemical Industries, Ltd. (JP) 2005-09-14 EP disclosed
EP-1574494-A1 Adamantane derivative Daicel Chemical Industries, Ltd. (JP) 2005-09-14 EP disclosed
US-20050158662-A1 Adamantane derivatives and resin compositions using the same as raw material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-07-21 US disclosed
US-6468487-B1 SUCH AS N-HYDROXYPHTHALIMIDE; DIRECTLY AND EFFICIENTLY REACTING ADAMANTANE WITH NITROGEN OXIDE OR WITH CARBON MONOXIDE AND OXYGEN DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-10-22 US disclosed
US-6392104-B1 CHEMICAL INTERMEDIATES FOR DRUGS, AGRICULTURE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-05-21 US disclosed
JP-2001354618-A METHOD FOR PRODUCING DI-TERT-BUTYL 1, 3- ADAMANTANEDICARBOXYLATE IDEMITSU PETROCHEM CO LTD 2001-12-25 JP disclosed
EP-0927711-A1 ADAMANTANE DERIVATIVES AND PROCESS FOR PRODUCING THEM Daicel Chemical Industries, Ltd. (JP) 1999-07-07 EP disclosed
EP-0897747-A1 NITRATION OR CARBOXYLATION CATALYSTS Daicel Chemical Industries, Ltd. (JP) 1999-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250066288-A1 DIHYDRAZIDE-DIHYDRAZONE COMPOUNDS WITH ADAMANTYL MOIETY AND A PROCESS FOR SYNTHESIS OF THE SAME DHODH, TALDO1, SLC5A1 NPSR1 2114/4885GLA 590/4885THRB 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.