Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | DHFR | P00374 | 3/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303133 | 0.92 | DHFR (0.74) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL16305289 | 0.92 | DHFR (0.74) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL16303127 | 0.90 | LMNA (0.68) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL14905233 | 0.87 | MAPT (0.74) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL16303131 | 0.87 | MAPT (0.74) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL31666744 | 0.84 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL404777 | 0.84 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL29365023 | 0.84 | LMNA (1.00) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL404778 | 0.84 | LMNA (0.79) | LMNAMAPTPOLBMEN1KMT2A | |
| SCHEMBL29614640 | 0.84 | LMNA (0.79) | LMNAMAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140369933-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140369933-A1 | FLUORINE-18 LABELED HYDROGEN ION PROBES | FUCA2, FUCA1, CD68 | LMNA 4309/4885MAPT 1154/4885POLB 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.