Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303830 | 0.94 | TSHR (0.45) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL16303828 | 0.90 | MAPT (0.39) | TSHRBCHEACHESERPINE1ALDH1A1 | |
| SCHEMBL2604388 | 0.84 | TSHR (0.46) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL16303827 | 0.84 | BCHE (0.43) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL21454582 | 0.82 | KIF11 (0.45) | TSHRSERPINE1ALDH1A1KDM4ETDP1 | |
| SCHEMBL11998153 | 0.82 | BCHE (0.50) | BCHEACHEALDH1A1KDM4ETDP1 | |
| SCHEMBL14900745 | 0.82 | BCHE (0.50) | BCHEACHEALDH1A1KDM4ETDP1 | |
| SCHEMBL25490702 | 0.76 | KIF11 (0.46) | TSHRBCHEACHEALDH1A1KDM4E | |
| SCHEMBL25917038 | 0.76 | ALDH1A1 (0.47) | BCHEACHEALDH1A1KDM4EHPGD | |
| SCHEMBL25523207 | 0.75 | GRM2 (0.44) | SERPINE1ALDH1A1KDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993708-B2 | Carbazole polymer | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140371421-A1 | CARBAZOLE POLYMER | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2014-12-18 | — | — | US | disclosed |