Sugi Predict

Sugi Predict / Compounds / SCHEMBL1630438

SCHEMBL1630438

SCHEMBL1630438

CCCCCCCCOc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTPN11 Q06124 5/20 0.52
▸ RARB P10826 3/20 0.50
▸ NR5A1 Q13285 1/20 0.48
▸ PTPN1 P18031 1/20 0.47
▸ PDK2 Q15119 1/20 0.45
▸ LMNA P02545 1/20 0.44
▸ GAA P10253 1/20 0.44
▸ MAPK10 P53779 1/20 0.44
▸ CNR1 P21554 1/20 0.44
▸ CNR2 P34972 1/20 0.44
▸ GPR55 Q9Y2T6 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5550301 1.00 PTPN11 (0.52) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL31425691 1.00 PTPN11 (0.52) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL10090875 1.00 PTPN11 (0.52) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL10090891 1.00 PTPN11 (0.52) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL38951 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL7887565 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL7125656 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL4215764 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL1467411 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2
SCHEMBL1468260 0.97 PTPN11 (0.54) PTPN11RARBNR5A1PTPN1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8585782-B2 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-11-19 — — US disclosed
US-8585782-B2 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-11-19 — — US disclosed
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-06-27 — — US disclosed
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-06-27 — — US disclosed
WO-2012034932-A1 USE OF SPECIFIC BIS(BIPHENYL)TRIAZINE DERIVATIVES AND MIXTURES THEREOF AS UV ABSORBERS BASF SE (DE) 2012-03-22 — — WO disclosed
US-20110089384-A1 HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER LAZZARI DARIO 2011-04-21 — — US disclosed
US-7476699-B2 Amino- and hydroxysubstituted triphenyl-s-triazines as stabilizers CIBA SPECIALTY CHEMICALS CORP. (US) 2009-01-13 — — US disclosed
EP-1892262-A1 Highly compatible and non-migratory polymeric UV-Absorber Ciba Specialty Chemicals Holding Inc. (CH) 2008-02-27 — — EP disclosed
EP-1627011-B1 HIGHLY COMPATIBLE AND NON-MIGRATORY POLYMERIC UV-ABSORBER CIBA SC HOLDING AG (CH) 2007-12-19 — — EP disclosed
US-20070274933-A1 Amino- and hydroxysubstituted triphenyl-S-triazines as stabilizers REINEHR DIETER 2007-11-29 — — US disclosed
WO-2002048118-A1 BENZOPHENONE UV-ABSORBERS WITH HETEROCYCLIC SUBSTITUENTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-06-20 — — WO disclosed
WO-2002028854-A1 HETEROARYL SUBSTITUTED HYDROXYPHENYLTRIAZINE UV-ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-04-11 — — WO disclosed
US-20010039341-A1 Biphenyl-Substituted Triazines FLETCHER IAN JOHN (CH) 2001-11-08 — — US disclosed
WO-2001057126-A1 CANDLE WAX STABILIZED BY A COMBINATION OF UV ABSORBER PLUS A SELECTED HINDERED AMINE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-09 — — WO disclosed
US-6255483-B1 USEFUL AS LIGHT STABILIZERS FOR TEXTILE FIBER MATERIALS AND SUNSCREENS FOR HUMAN SKIN CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-03 — — US disclosed
EP-1021421-A1 AMINO- AND HYDROXYSUBSTITUTED TRIPHENYL-S-TRIAZINES AS STABILIZERS Ciba SC Holding AG (CH) 2000-07-26 — — EP disclosed
US-5998116-A TRIAZINE UV ABSORBERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-12-07 — — US disclosed
EP-0815089-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER Ciba SC Holding AG (CH) 1998-01-07 — — EP disclosed
WO-1997036880-A1 AMINO- AND HYDROXYSUBSTITUTED TRIPHENYL-S-TRIAZINES AS STABILIZERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-10-09 — — WO disclosed
WO-1996028431-A1 BIPHENYL-SUBSTITUTED TRIAZINES AS LIGHT STABILIZER CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-09-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070274933-A1 Amino- and hydroxysubstituted triphenyl-S-triazines as stabilizers AHR, HRH4, HRH2 PTPN11 2768/4885RARB 2933/4885NR5A1 4504/4885
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers NR1H2, CBR3, NR1H3 PTPN11 1118/4885RARB 137/4885NR5A1 312/4885
US-20010039341-A1 Biphenyl-Substituted Triazines TYR, CYP1B1, NFE2L2 PTPN11 2496/4885RARB 1218/4885NR5A1 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.