⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394820 | 0.78 | — | — | |
| SCHEMBL152294 | 0.78 | — | — | |
| SCHEMBL9195093 | 0.78 | BACE1 (0.31) | — | |
| SCHEMBL31128745 | 0.78 | — | — | |
| Water SCHEMBL9340526 | 0.76 | — | — | |
| Water SCHEMBL9340500 | 0.76 | LOXL2 (0.33) | — | |
| Phosphine SCHEMBL8190663 | 0.76 | — | — | |
| SCHEMBL28152481 | 0.76 | — | — | |
| SCHEMBL31254070 | 0.76 | — | — | |
| SCHEMBL27906547 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605080-A1 | TREATMENT OF MITOCHONDRIAL DISEASES WITH SGC STIMULATORS | Tisento Therapeutics Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| US-20240207265-A1 | TREATMENT OF CNS DISEASES WITH sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2024-06-27 | — | — | US | disclosed |
| CN-117957228-A | SGC stimulators | 帝善多制药公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2024086182-A1 | TREATMENT OF MITOCHONDRIAL DISEASES WITH SGC STIMULATORS | TISENTO THERAPEUTICS INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| CN-117915917-A | CNS disease treatment using sGC stimulators | 帝善多制药公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-4326722-A1 | SGC STIMULATORS | Tisento Therapeutics Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| EP-4326268-A1 | TREATMENT OF CNS DISEASES WITH SGC STIMULATORS | Tisento Therapeutics Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| WO-2022225902-A1 | TREATMENT OF CNS DISEASES WITH SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| WO-2022225903-A1 | SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. (US) | 2022-10-27 | — | — | WO | disclosed |
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-12 | — | — | US | disclosed |
| US-8101753-B2 | Production method of pyrimidine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20080039445-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |