Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL82388 | 0.82 | MMP2 (0.38) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL82390 | 0.82 | MMP2 (0.38) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL82389 | 0.82 | MMP2 (0.38) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL82676 | 0.82 | MMP2 (0.38) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL82677 | 0.82 | MMP2 (0.38) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL10074248 | 0.78 | ACACB (0.36) | SMN1; SMN2MEN1ALDH1A1KMT2ALRRK2 | |
| SCHEMBL84196 | 0.73 | ACACB (0.30) | — | |
| SCHEMBL84197 | 0.73 | ACACB (0.30) | — | |
| SCHEMBL83888 | 0.73 | ACACB (0.30) | — | |
| SCHEMBL83890 | 0.73 | ACACB (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088914-A1 | PRODUCTION METHOD OF PYRIMIDINE COMPOUNDS | DPYD, DHFR, DHODH | SMN1; SMN2 2172/4885MEN1 4322/4885ALDH1A1 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.