Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CALML3 | P27482 | 5/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SDHA | P31040 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177016 | 0.84 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394291 | 0.84 | MAOA (0.65) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394141 | 0.76 | MAOA (0.62) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL2899124 | 0.70 | MAOA (0.68) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL11983103 | 0.70 | CALML3 (0.42) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14386911 | 0.69 | BPTF (0.43) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL11983134 | 0.69 | MAOA (0.40) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL14432626 | 0.69 | MAOA (0.66) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3178893 | 0.69 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393425 | 0.69 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660465-B1 | PROCESS FOR THE SYNTHESIS OF BIARYL OXAZOLIDINONES | MELINTA THERAPEUTICS INC (US) | 2014-12-17 | — | — | EP | disclosed |