SCHEMBL16307758

SCHEMBL16307758

c1ccc(-n2c3ccccc3c3cc(-c4ccc5cc(-c6cc7cccc8c(-c9ccc%10c(c9)c9ccccc9n%10-c9ccccc9)cc9cccc6c9c78)c6cccc7ccc4c5c76)ccc32)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 2/20 0.37
ERBB2 P04626 1/20 0.37
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
ACHE P22303 1/20 0.37
AHR P35869 1/20 0.37
PTGER4 P35408 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 2/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
PTGES O14684 1/20 0.32
HDAC4 P56524 1/20 0.31
KMT2A Q03164 3/20 0.31
IL1R1 P14778 1/20 0.31
TSHR P16473 2/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25916810 0.94 KDM4E (0.41) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL21190613 0.94 L3MBTL1 (0.47) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL16307757 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL27365580 0.92 L3MBTL1 (0.51) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL21190562 0.92 L3MBTL1 (0.51) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL27365680 0.91 L3MBTL1 (0.47) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL16283221 0.90 L3MBTL1 (0.46) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL3181107 0.90 L3MBTL1 (0.40) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL13417862 0.89 KDM4E (0.43) L3MBTL1KDM4EATMCYP1A2ERBB2
SCHEMBL25667533 0.89 KDM4E (0.43) L3MBTL1KDM4EATMCYP1A2ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014200243-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME SK CHEMICALS CO., LTD. (KR) 2014-12-18 WO disclosed