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SCHEMBL16309301

SCHEMBL16309301

O=C(CCCS(=O)(=O)NC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)NCCCC(=O)NC(CCC(=O)NC(CCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NP)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.49
▸ FOLH1 Q04609 2/20 0.35
▸ CCKAR P32238 9/20 0.35
▸ CCKBR P32239 9/20 0.35
▸ GLO1 Q04760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16309319 0.93 GLP1R (0.42) GLP1RFOLH1GLO1
SCHEMBL24734313 0.91 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL12981346 0.91 GLP1R (0.49) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL20567323 0.90 GLP1R (0.45) GLP1RFOLH1CCKARCCKBR
SCHEMBL20567326 0.90 GLP1R (0.45) GLP1RFOLH1CCKARCCKBR
SCHEMBL12122193 0.90 GLP1R (0.46) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL13569766 0.90 GLP1R (0.46) GLP1RCCKARCCKBR
SCHEMBL13034771 0.90 GLP1R (0.48) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL13034770 0.90 GLP1R (0.48) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL16408121 0.90 GLP1R (0.48) GLP1RFOLH1CCKARCCKBRGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2190460-B1 PEPTIDES DERIVATIZED WITH A-B-C-D- AND THEIR THERAPEUTICAL USE NOVO NORDISK AS (DK) 2014-12-17 — — EP disclosed
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