SCHEMBL20567323

SCHEMBL20567323

O=C(CBr)NCCCC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CCCS(=O)(=O)NC(=O)CCCCCCCCCCCCCCCCc1nnn[nH]1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.45
▸ FOLH1 Q04609 2/20 0.35
▸ CCKAR P32238 9/20 0.34
▸ CCKBR P32239 9/20 0.34
▸ ALB P02768 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567326 1.00 GLP1R (0.45) GLP1RFOLH1CCKARCCKBRALB
SCHEMBL16478843 0.94 GLP1R (0.45) GLP1RFOLH1CCKARCCKBRALB
SCHEMBL19271209 0.94 GLP1R (0.45) GLP1RFOLH1CCKARCCKBRALB
SCHEMBL15849999 0.94 GLP1R (0.45) GLP1RFOLH1CCKARCCKBRALB
SCHEMBL16809355 0.92 GLP1R (0.50) GLP1RFOLH1ALB
SCHEMBL24734313 0.90 GLP1R (0.51) GLP1RCCKARCCKBR
SCHEMBL16309301 0.90 GLP1R (0.49) GLP1RFOLH1CCKARCCKBR
SCHEMBL27122639 0.89 CA12 (0.31) GLP1R
SCHEMBL12981346 0.89 GLP1R (0.49) GLP1RFOLH1CCKARCCKBR
SCHEMBL21242921 0.89 GLP1R (0.48) GLP1RFOLH1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 — — US disclosed
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 — — US disclosed
EP-3630805-A1 MIC-1 COMPOUNDS AND USES THEREOF Novo Nordisk A/S (DK) 2020-04-08 — — EP disclosed
US-20200079829-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK A/S (DK) 2020-03-12 — — US disclosed
US-10398782-B2 MIC-1 compounds and uses thereof NOVO NORDISK A/S (DK) 2019-09-03 — — US disclosed
US-10398782-B2 MIC-1 compounds and uses thereof NOVO NORDISK A/S (DK) 2019-09-03 — — US disclosed
US-20180339057-A1 MIC-1 Compounds and Uses Thereof NOVO NORDISK A/S (DK) 2018-11-29 — — US disclosed
WO-2018215525-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK A/S (DK) 2018-11-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079829-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 GLP1R 710/4885FOLH1 1511/4885CCKAR 1112/4885
US-10398782-B2 MIC-1 compounds and uses thereof IMMT, MICA, TAP1 GLP1R 710/4885FOLH1 1511/4885CCKAR 1112/4885
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 GLP1R 710/4885FOLH1 1511/4885CCKAR 1112/4885
US-20180339057-A1 MIC-1 Compounds and Uses Thereof IMMT, MICA, TAP1 GLP1R 710/4885FOLH1 1511/4885CCKAR 1112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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