Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16310139 | 0.89 | HDAC6 (0.34) | NLRP3TSHR | |
| SCHEMBL19123170 | 0.85 | SMN1; SMN2 (0.35) | NLRP3SMN1; SMN2TP53TSHRCYP1A2 | |
| SCHEMBL3337001 | 0.85 | SMN1; SMN2 (0.35) | NLRP3SMN1; SMN2TP53TSHRCYP1A2 | |
| SCHEMBL13246853 | 0.85 | SMN1; SMN2 (0.35) | NLRP3SMN1; SMN2TP53TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL3339489 | 0.84 | SMN1; SMN2 (0.34) | NLRP3SMN1; SMN2TP53TSHRCYP1A2 | |
| SCHEMBL13267843 | 0.84 | SMN1; SMN2 (0.39) | NLRP3SMN1; SMN2CYP1A2CYP2C9HIF1A | |
| SCHEMBL5810644 | 0.83 | TACR1 (0.39) | NLRP3SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL5810645 | 0.83 | TACR1 (0.39) | NLRP3SMN1; SMN2TP53MAPTLMNA | |
| SCHEMBL61919 | 0.82 | CPB2 (0.32) | — | |
| SCHEMBL61920 | 0.82 | CPB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8912185-B2 | Use of glutaric acid derivatives or the pharmaceutically acceptable salts thereof as anti-arrhythmic agents | Obschestvo S Ogranichennoi Otvetstvennostyu “Pharmenterprises” (RU) | 2014-12-16 | — | — | US | disclosed |