SCHEMBL61919

SCHEMBL61919

O=CNC(Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CPB2 Q96IY4 5/20 0.32
▸ CPB1 P15086 1/20 0.32
▸ EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61920 1.00 CPB2 (0.32) CPB2CPB1EPHX1
Pyrene SCHEMBL28035477 0.89 PIN1 (0.35) EPHX1
SCHEMBL5893971 0.87 CPB2 (0.32) CPB2CPB1
SCHEMBL5893967 0.87 CPB2 (0.32) CPB2CPB1
Hydrochloric Acid SCHEMBL31172342 0.85 CPB2 (0.31) CPB2CPB1
SCHEMBL16310139 0.84 HDAC6 (0.34) —
SCHEMBL30611740 0.84 CPB2 (0.33) CPB2CPB1
SCHEMBL3378638 0.83 CPB2 (0.34) CPB2CPB1
Hydrochloric Acid SCHEMBL30634622 0.83 CPB2 (0.34) CPB2CPB1
SCHEMBL3378642 0.83 CPB2 (0.34) CPB2CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3250191-B1 TABLETS COMPRISING GLP-1 AGONIST AND ENTERIC COATING NOVO NORDISK AS (DK) 2024-01-17 — — EP claimed
CN-109922835-B DCHBS active ester of PEG compound and application thereof 诺和诺德股份有限公司 2023-08-04 — — CN claimed
EP-2637698-B1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2022-04-20 — — EP claimed
CN-107108714-B GLP-1 derivatives and uses thereof 诺和诺德股份有限公司 2022-02-08 — — CN claimed
US-11117947-B2 Double-acylated GLP-1 derivatives NOVO NORDISK A/S (DK) 2021-09-14 — — US claimed
US-11034746-B2 Double-acylated GLP-1 derivatives NOVO NORDISK A/S (DK) 2021-06-15 — — US claimed
US-10946074-B2 GLP-1 derivatives and uses thereof NOVO NORDISK A/S (DK) 2021-03-16 — — US claimed
US-10689429-B2 Double-acylated GLP-1 compounds NOVO NORDISK A/S (DK) 2020-06-23 — — US claimed
US-10604554-B2 Double-acylated GLP-1 derivatives NOVO NORDISK A/S (DK) 2020-03-31 — — US claimed
US-20200079834-A1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2020-03-12 — — US claimed
WO-2013167455-A1 DOUBLE-ACYLATED GLP-1 DERIVATIVES NOVO NORDISK A/S (DK) 2013-11-14 — — WO claimed
US-20130288960-A1 Double-Acylated GLP-1 Derivatives NOVO NORDISK A/S (DK) 2013-10-31 — — US claimed
US-20120295847-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2012-11-22 — — US claimed
EP-1863839-B1 ACYLATED GLP-1 COMPOUNDS NOVO NORDISK AS (DK) 2010-08-04 — — EP claimed
US-20090156478-A1 Acylated GLP-1 Compounds NOVO NORDISK A/S (DK) 2009-06-18 — — US claimed
US-20080207507-A1 Extended Glp-1 Compounds NOVO NORDISK A/S (DK) 2008-08-28 — — US claimed
EP-1863521-A1 EXTENDED GLP-1 COMPOUNDS Novo Nordisk A/S (DK) 2007-12-12 — — EP claimed
EP-1863839-A2 ACYLATED GLP-1 COMPOUNDS NOVO NORDISK A/S (DK) 2007-12-12 — — EP claimed
WO-2006097537-A2 ACYLATED GLP-1 COMPOUNDS NOVO NORDISK A/S (DK) 2006-09-21 — — WO claimed
WO-2006097538-A1 EXTENDED GLP-1 COMPOUNDS NOVO NORDISK A/S (DK) 2006-09-21 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207507-A1 Extended Glp-1 Compounds GLP1R, GIPR, IAPP CPB2 2455/4885CPB1 1157/4885EPHX1 3005/4885
US-20090156478-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR CPB2 3200/4885CPB1 1837/4885EPHX1 3672/4885
US-10604554-B2 Double-acylated GLP-1 derivatives GLP1R, GIPR, GPR119 CPB2 3610/4885CPB1 3560/4885EPHX1 2733/4885
US-20120295847-A1 Acylated GLP-1 Compounds GLP1R, GIPR, GCGR CPB2 3200/4885CPB1 1837/4885EPHX1 3672/4885
US-11117947-B2 Double-acylated GLP-1 derivatives GLP1R, SLC5A1, IAPP CPB2 4393/4885CPB1 3963/4885EPHX1 3870/4885
US-11034746-B2 Double-acylated GLP-1 derivatives GLP1R, SLC5A1, IAPP CPB2 4353/4885CPB1 3969/4885EPHX1 3949/4885
US-20130288960-A1 Double-Acylated GLP-1 Derivatives GLP1R, VIP, IAPP CPB2 3334/4885CPB1 2694/4885EPHX1 3822/4885
US-20200079834-A1 DOUBLE-ACYLATED GLP-1 DERIVATIVES GLP1R, SLC5A1, IAPP CPB2 4393/4885CPB1 3963/4885EPHX1 3870/4885
US-10689429-B2 Double-acylated GLP-1 compounds GLP1R, GIPR, GPR119 CPB2 2080/4885CPB1 1356/4885EPHX1 2760/4885
US-10946074-B2 GLP-1 derivatives and uses thereof GLP1R, DPP8, DPP7 CPB2 1968/4885CPB1 1672/4885EPHX1 3939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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