Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTM2 | P28161 | 1/20 | 0.54 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17788964 | 0.91 | GSTM2 (0.47) | GSTM2BCL6BCORMEN1KMT2A | |
| SCHEMBL12432365 | 0.86 | GSTM2 (0.42) | GSTM2MEN1KMT2AHTTHDAC3 | |
| SCHEMBL15507622 | 0.85 | GSTM2 (0.43) | GSTM2MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12966304 | 0.84 | GSTM2 (0.44) | GSTM2MEN1KMT2AHTTHDAC3 | |
| SCHEMBL15507618 | 0.83 | HDAC3 (0.47) | GSTM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15507466 | 0.83 | HDAC3 (0.47) | GSTM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15507616 | 0.83 | HDAC3 (0.47) | GSTM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15507465 | 0.83 | HDAC3 (0.47) | GSTM2MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13438510 | 0.82 | GSTM2 (0.39) | GSTM2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12241928 | 0.81 | GSTM2 (0.44) | GSTM2MEN1KMT2AHTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014201405-A1 | NOVEL ALLOSTERIC INHIBITORS OF PROTEASOME AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-18 | — | — | WO | disclosed |