Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTM2 | P28161 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | BCL6 | P41182 | 1/20 | 0.35 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16310249 | 0.91 | GSTM2 (0.54) | GSTM2MAPTALDH1A1POLBHDAC3 | |
| SCHEMBL13438510 | 0.85 | GSTM2 (0.39) | GSTM2MAPTALDH1A1HDAC3HDAC4 | |
| SCHEMBL12432365 | 0.82 | GSTM2 (0.42) | GSTM2POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL15507622 | 0.82 | GSTM2 (0.43) | GSTM2GAAALDH1A1POLBHDAC3 | |
| SCHEMBL12966304 | 0.81 | GSTM2 (0.44) | GSTM2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15507621 | 0.81 | MEN1 (0.36) | GSTM2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL15507618 | 0.80 | HDAC3 (0.47) | GSTM2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL15507466 | 0.80 | HDAC3 (0.47) | GSTM2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL15507616 | 0.80 | HDAC3 (0.47) | GSTM2ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL15507465 | 0.80 | HDAC3 (0.47) | GSTM2ALDH1A1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160152567-A1 | NOVEL ALLOSTERIC INHIBITORS OF PROTEASOME AND METHODS OF USE THEREOF | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SY STEM (US) | 2016-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160152567-A1 | NOVEL ALLOSTERIC INHIBITORS OF PROTEASOME AND METHODS OF USE THEREOF | PSME3, PSMB1, PSMB2 | GSTM2 1955/4885MAPT 2575/4885GAA 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.