Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | LIG1 | P18858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CES1 | P23141 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716498 | 0.89 | LIG1 (0.59) | ALDH1A1LIG1SMN1; SMN2HTTLMNA | |
| SCHEMBL12792043 | 0.85 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL31333081 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL1786654 | 0.82 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL15197083 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL5710147 | 0.81 | HTT (0.66) | ALDH1A1LIG1SMN1; SMN2HTTCES2 | |
| SCHEMBL6354092 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL30375558 | 0.81 | HTT (0.66) | ALDH1A1LIG1SMN1; SMN2HTTCES2 | |
| SCHEMBL21802003 | 0.80 | LIG1 (0.87) | ALDH1A1LIG1SMN1; SMN2HTTLMNA | |
| SCHEMBL29499085 | 0.80 | LIG1 (0.87) | ALDH1A1LIG1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664128-B1 | WATER BASED CONCENTRATED PRODUCT FORMS OF LIGHT STABILIZERS MADE BY A HETEROPHASE POLYMERIZATION TECHNIQUE | CIBA HOLDING INC (CH) | 2009-01-21 | — | — | EP | disclosed |