Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5710147 | 1.00 | HTT (0.66) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11028801 | 0.84 | MEN1 (0.61) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL10735111 | 0.83 | MEN1 (0.81) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL30375015 | 0.82 | KMT2A (0.68) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1101897 | 0.82 | KMT2A (0.68) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13557813 | 0.82 | ALDH1A1 (0.57) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL93420 | 0.81 | MEN1 (0.78) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL29375096 | 0.81 | MEN1 (0.78) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL16313232 | 0.81 | ALDH1A1 (0.70) | HTTSMN1; SMN2ALDH1A1MAPTNPC1 | |
| SCHEMBL29450505 | 0.80 | MEN1 (0.65) | HTTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |