Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PREP | P48147 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316793 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2F2PREPCTSK | |
| SCHEMBL15805130 | 1.00 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2F2PREPCTSK | |
| SCHEMBL17015163 | 0.95 | PREP (0.47) | ALDH1A1SMN1; SMN2F2PREPCTSK | |
| SCHEMBL29503770 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL29047047 | 0.89 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL29549607 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL29378245 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL29503800 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL118354 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A | |
| SCHEMBL119560 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2F2PREPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | ALDH1A1 1079/4885SMN1; SMN2 2049/4885F2 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.