Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16316793 | 0.95 | ALDH1A1 (0.44) | PREPF2ALDH1A1SMN1; SMN2CTSK | |
| SCHEMBL15805130 | 0.95 | ALDH1A1 (0.44) | PREPF2ALDH1A1SMN1; SMN2CTSK | |
| SCHEMBL16316767 | 0.95 | ALDH1A1 (0.44) | PREPF2ALDH1A1SMN1; SMN2CTSK | |
| SCHEMBL30139033 | 0.90 | ALDH1A1 (0.53) | PREPF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29074158 | 0.90 | ALDH1A1 (0.53) | PREPF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28510226 | 0.90 | ALDH1A1 (0.53) | PREPF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17020369 | 0.89 | PREP (0.48) | PREPF2ALDH1A1 | |
| SCHEMBL29378245 | 0.84 | ALDH1A1 (0.58) | PREPF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL29549607 | 0.84 | ALDH1A1 (0.58) | PREPF2ALDH1A1SMN1; SMN2 | |
| SCHEMBL119560 | 0.84 | ALDH1A1 (0.58) | PREPF2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | UNIV NEW YORK (US) | 2017-08-31 | — | — | US | disclosed |
| US-9593142-B2 | Aldehyde capture ligation technology for synthesis of amide bonds | NEW YORK UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | NEW YORK UNIVERSITY (US) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247324-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | PREP 1036/4885F2 1690/4885ALDH1A1 3/4885 |
| US-20150232504-A1 | ALDEHYDE CAPTURE LIGATION TECHNOLOGY FOR SYNTHESIS OF AMIDE BONDS | ALDH3A1, ALDH2, ALDH1A1 | PREP 1036/4885F2 1690/4885ALDH1A1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.