Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CPS1 | P31327 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319300 | 0.76 | FFAR1 (0.48) | HTTFFAR1 | |
| SCHEMBL16318824 | 0.74 | ALDH1A1 (0.45) | KDM4EHTTSMN1; SMN2FFAR1POLQ | |
| SCHEMBL2312339 | 0.74 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL25189947 | 0.72 | DHODH (0.47) | SMN1; SMN2L3MBTL1FFAR1POLQCPS1 | |
| SCHEMBL16318901 | 0.71 | FFAR1 (0.53) | FFAR1 | |
| SCHEMBL2314852 | 0.71 | FFAR1 (0.48) | SMN1; SMN2FFAR1 | |
| SCHEMBL16319293 | 0.70 | NPC1 (0.39) | ELANEKDM4EFFAR1POLQ | |
| SCHEMBL16318838 | 0.70 | PIK3CD (0.36) | ELANEKDM4EFFAR1 | |
| SCHEMBL22101080 | 0.70 | ELANE (0.56) | ELANE | |
| SCHEMBL12221638 | 0.69 | FFAR1 (0.44) | SMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |