Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLQ | O75417 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319268 | 0.87 | GUSB (0.41) | NPC1MAPTRAB9APOLQALDH1A1 | |
| SCHEMBL16318872 | 0.78 | GUSB (0.41) | NPC1MAPTRAB9A | |
| SCHEMBL16318838 | 0.77 | PIK3CD (0.36) | MAPTALDH1A1HPGDFFAR1CA2 | |
| SCHEMBL15081838 | 0.71 | ALDH1A1 (0.40) | NPC1MAPTRAB9AALDH1A1RXFP1 | |
| SCHEMBL16318752 | 0.71 | FFAR1 (0.42) | FFAR1KMT2A | |
| SCHEMBL16318649 | 0.71 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL16319124 | 0.70 | ELANE (0.39) | POLQFFAR1ELANEKDM4E | |
| SCHEMBL22101080 | 0.68 | ELANE (0.56) | MEN1KMT2ACA2ELANE | |
| SCHEMBL10483703 | 0.66 | ELANE (0.56) | NPC1MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL18490124 | 0.65 | OPRD1 (0.50) | MAPTRAB9APOLQALDH1A1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |