Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318804 | 0.99 | FFAR1 (0.35) | FFAR1ESR1ESR2TNIK | |
| SCHEMBL16319294 | 0.98 | FFAR1 (0.36) | FFAR1ESR1ESR2PIK3CDPIK3CB | |
| SCHEMBL16318844 | 0.85 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL16318652 | 0.82 | SMN1; SMN2 (0.32) | FFAR1 | |
| SCHEMBL16319169 | 0.80 | BACE1 (0.33) | FFAR1 | |
| SCHEMBL16318556 | 0.77 | ESR1 (0.39) | FFAR1ESR1ESR2PIK3CDPIK3CB | |
| SCHEMBL16319322 | 0.76 | FFAR1 (0.36) | FFAR1 | |
| SCHEMBL16319295 | 0.75 | FFAR1 (0.35) | FFAR1ESR1ESR2TNIK | |
| SCHEMBL16319224 | 0.75 | FFAR1 (0.40) | FFAR1ESR1ESR2PIK3CDPIK3CB | |
| SCHEMBL16318997 | 0.74 | FFAR1 (0.65) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |