Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318834 | 0.85 | FFAR1 (0.44) | FFAR1 | |
| SCHEMBL16319225 | 0.79 | FFAR1 (0.39) | FFAR1TNIKGRIN1GRIN2BESR1 | |
| SCHEMBL16319060 | 0.78 | FFAR1 (0.47) | FFAR1 | |
| SCHEMBL16319250 | 0.75 | FFAR1 (0.36) | FFAR1TNIKESR1ESR2 | |
| SCHEMBL16318804 | 0.74 | FFAR1 (0.35) | FFAR1TNIKESR1ESR2GAA | |
| SCHEMBL15213181 | 0.74 | FFAR1 (0.65) | FFAR1 | |
| SCHEMBL16319294 | 0.73 | FFAR1 (0.36) | FFAR1TNIKESR1ESR2 | |
| SCHEMBL16318863 | 0.72 | FFAR1 (0.38) | FFAR1ALDH1A1GAA | |
| SCHEMBL16318775 | 0.71 | FFAR1 (0.43) | FFAR1ALDH1A1TNIKESR1ESR2 | |
| SCHEMBL16319229 | 0.71 | FFAR1 (0.40) | FFAR1ALDH1A1GRIN1GRIN2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |