SCHEMBL16319282

SCHEMBL16319282

CNC(=O)C(=N/OC)/C(C)=C/COc1ccn(-c2ccc(Cl)c(F)c2)n1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 16/20 0.39
KCNH2 Q12809 1/20 0.39
MET P08581 1/20 0.34
ACKR3 P25106 1/20 0.33
NOTUM Q6P988 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16319284 1.00 SIGMAR1 (0.39) SIGMAR1KCNH2METACKR3NOTUM
SCHEMBL16319286 1.00 SIGMAR1 (0.39) SIGMAR1KCNH2METACKR3NOTUM
SCHEMBL16319175 0.93 SIGMAR1 (0.39) SIGMAR1KCNH2
SCHEMBL16319174 0.93 SIGMAR1 (0.39) SIGMAR1KCNH2
SCHEMBL16319177 0.93 SIGMAR1 (0.39) SIGMAR1KCNH2
SCHEMBL16319191 0.92 SIGMAR1 (0.46) SIGMAR1KCNH2NOTUM
SCHEMBL16319190 0.92 SIGMAR1 (0.46) SIGMAR1KCNH2NOTUM
SCHEMBL16319188 0.92 SIGMAR1 (0.46) SIGMAR1KCNH2NOTUM
SCHEMBL19579930 0.89 KCNH2 (0.30) SIGMAR1KCNH2
SCHEMBL16318777 0.89 KCNH2 (0.30) SIGMAR1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US claimed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US claimed
EP-3010344-B1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-11-15 EP claimed
US-9763448-B2 Fungicidal mixtures I comprising strobilurin-type fungicides BASF SE (DE) 2017-09-19 US claimed
EP-2815650-B1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2016-08-17 EP claimed
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF Agro B.V. (NL) 2016-05-19 US claimed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP claimed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US disclosed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US disclosed
EP-3267797-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-01-17 EP disclosed
EP-3010344-B1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-11-15 EP disclosed
US-9763448-B2 Fungicidal mixtures I comprising strobilurin-type fungicides BASF SE (DE) 2017-09-19 US disclosed
WO-2015036058-A1 FUNGICIDAL PYRIMIDINE COMPOUNDS BASF SE (DE) 2015-03-19 WO disclosed
WO-2015036059-A1 FUNGICIDAL PYRIMIDINE COMPOUNDS BASF SE (DE) 2015-03-19 WO disclosed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP disclosed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed
WO-2014202421-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2014-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, STS, SNX1 SIGMAR1 3797/4885KCNH2 803/4885MET 2893/4885
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES STS, SNX1, SFXN1 SIGMAR1 3281/4885KCNH2 1450/4885MET 3546/4885
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, SNX3, SFXN3 SIGMAR1 3647/4885KCNH2 894/4885MET 3056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.