Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.53 |
| ▸ | PNLIP | P16233 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679375 | 0.92 | SCN9A (0.58) | SCN9APNLIPSCN5A | |
| SCHEMBL678837 | 0.88 | SCN9A (0.59) | SCN9APNLIP | |
| SCHEMBL679932 | 0.88 | SCN9A (0.51) | SCN9APNLIPSCN5A | |
| SCHEMBL680358 | 0.88 | SCN9A (0.64) | SCN9APNLIPSCN5A | |
| SCHEMBL678799 | 0.87 | SCN9A (0.56) | SCN9ASCN5A | |
| SCHEMBL680835 | 0.86 | SCN9A (0.61) | SCN9ASCN5A | |
| SCHEMBL679029 | 0.86 | SCN9A (0.56) | SCN9A | |
| SCHEMBL681070 | 0.86 | SCN9A (0.58) | SCN9ASCN5A | |
| SCHEMBL16319549 | 0.85 | SCN9A (0.58) | SCN9ASCN5A | |
| SCHEMBL16319859 | 0.84 | MMP1 (0.56) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593427-B1 | SULFONAMIDE DERIVATIVES AS NAV1.7 INHIBITORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2014-12-24 | — | — | EP | disclosed |