M-Xylene

M-Xylene

SCHEMBL163239

Cc1cccc(C)c1.N=C=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.67
ALDH1A1 P00352 2/20 0.46
MAPK1 P28482 1/20 0.46
PARP1 P09874 1/20 0.43
TSHR P16473 1/20 0.43
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MGLL Q99685 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL31383510 1.00 ACHE (0.67) ACHEALDH1A1MAPK1PARP1TSHR
M-Xylene SCHEMBL28204206 1.00 ACHE (0.67) ACHEALDH1A1MAPK1PARP1TSHR
M-Xylene SCHEMBL27020 1.00 ACHE (0.67) ACHEALDH1A1MAPK1PARP1TSHR
M-Xylene SCHEMBL4769348 0.97 ACHE (0.63) ACHEALDH1A1MAPK1PARP1TSHR
M-Xylene SCHEMBL28613777 0.93 ACHE (0.57) ACHEALDH1A1MAPK1PARP1TSHR
M-Xylene SCHEMBL28493229 0.91 ACHE (0.55) ACHEALDH1A1MAPK1PARP1TDP1
Naphthalene SCHEMBL27950601 0.91 ACHE (0.55) ACHEALDH1A1MAPK1PARP1TSHR
Naphthalene SCHEMBL9068412 0.91 ACHE (0.55) ACHEALDH1A1MAPK1PARP1TSHR
SCHEMBL476272 0.89 ACHE (0.52) ACHEALDH1A1MAPK1PARP1TSHR
SCHEMBL8759875 0.89 ACHE (0.52) ACHEALDH1A1MAPK1PARP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3595 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3916471-B1 PLASTIC LENS AND EYE GLASSES TOKAI OPTICAL CO LTD (JP) 2025-11-12 EP claimed
US-12318748-B2 Microcapsules for use with polyurethane and epoxy adhesives THE JOHNS HOPKINS UNIVERSITY (US) 2025-06-03 US claimed
CN-119968412-A Non-softening thermoplastic polyurethane 路博润先进材料公司 2025-05-09 CN claimed
CN-119907820-A Isocyanate composition 韩华思路信(株) 2025-04-29 CN claimed
CN-119335105-A Method for determining azo dye and isocyanate harmful substances in textile 深圳市艾溹技术研究有限公司 2025-01-21 CN claimed
US-20240287362-A1 ADHESIVE COATING COMPOSITION FOR ELECTRICAL STEEL SHEET, ELECTRICAL STEEL SHEET LAMINATE, AND MANUFACTURING METHOD THEREFOR POSCO CO., LTD (KR) 2024-08-29 US claimed
CN-115335442-B Microsphere coated polyurethane articles and methods of making the same 3M创新有限公司 2024-08-16 CN claimed
CN-117624965-B Low temperature curable ink composition for polarizer PET protective film 深圳博诺玛标识技术有限公司 2024-08-06 CN claimed
US-12049437-B2 Diisocyanate composition, preparation method thereof and optical material using same SK PUCORE CO., LTD. (KR) 2024-07-30 US claimed
CN-118317988-A Isocyanate composition and process for producing the same 韩华思路信(株) 2024-07-09 CN claimed
US-4622354-A IMPACT STRENGTH THE BUDD COMPANY (US) 1986-11-11 US claimed
US-4618632-A POLYESTERURETHANES, ACRYLATE REACTIVE DILUENT WESTINGHOUSE ELECTRIC CORP. (US) 1986-10-21 US claimed
US-4560617-A FERROMAGNETIC PARTICLES AND RADIATION POLYMERIZABLE RESIN BINDER TDK CORPORATION (JP) 1985-12-24 US claimed
US-4455340-A POLYURETHANE INOUE MTP KABUSHIKI KAISHA (JP) 1984-06-19 US claimed
US-4436859-A IMPROVED COMPRESSION MODULI AND RESIDUAL SET SOCIETE CHIMIQUE DES CHARBONNAGES S.A. (FR) 1984-03-13 US claimed
US-4285930-A Antigens comprising immunostimulant adjuvants and their use in immunotherapy LIKHITE VILAS V 1981-08-25 US claimed
US-4251229-A Stabilized fuel slurry DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1981-02-17 US claimed
US-4158378-A POLYCAPROLACTONE, POLYUREAS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-06-19 US claimed
US-4001290-A LACQUERS, COATINGS, ADHESIVES, TELOMERS, FOAM PLASTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
US-3945981-A COATINGS UNIROYAL, INC. (US) 1976-03-23 US claimed