Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97780 | 0.91 | TSHR (0.56) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL180144 | 0.88 | TSHR (0.53) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL1844352 | 0.88 | TSHR (0.53) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL1106829 | 0.86 | LMNA (0.74) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL95982 | 0.85 | TSHR (1.00) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL5067235 | 0.83 | TSHR (0.48) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Selenium SCHEMBL30845448 | 0.82 | TSHR (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL30845449 | 0.82 | TSHR (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Water SCHEMBL11221867 | 0.82 | TSHR (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 | |
| Ammonia Solution, Strong SCHEMBL8958644 | 0.82 | TSHR (0.93) | TSHRLMNAKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994280-B2 | disulfide bond formation in solid phase peptide synthesis; starting with a cysteine that is protected in its side chain by a S-tert-butyl-sulphenyl group and which is N-terminally substituted at its N.alpha. and 3,3'-dithio-propionimide; coupling, cyclization; Eptifibatide on Sieber resin | LONZA AG (CH) | 2011-08-09 | — | — | US | claimed |
| EP-1805203-B1 | ON-RESIN PEPTIDE CYCLIZATION | LONZA AG (CH) | 2010-01-13 | — | — | EP | claimed |
| US-20150247141-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | RANA THERAPEUTICS, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150247141-A1 | MULTIMERIC OLIGONUCLEOTIDE COMPOUNDS | RANA THERAPEUTICS, INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-8637277-B2 | Method for producing 3-mercaptopropionic acid or salt thereof | MITSUI CHEMICALS, INC. (JP) | 2014-01-28 | — | — | US | disclosed |
| US-8637277-B2 | Method for producing 3-mercaptopropionic acid or salt thereof | MITSUI CHEMICALS, INC. (JP) | 2014-01-28 | — | — | US | disclosed |
| EP-2426210-A1 | PROCESS FOR PRODUCTION OF 3-MERCAPTOPROPIONIC ACID OR SALT THEREOF | Mitsui Chemicals, Inc. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120040418-A1 | METHOD FOR PRODUCING 3-MERCAPTOPROPIONIC ACID OR SALT THEREOF | MITSUI CHEMICALS INC. (JP) | 2012-02-16 | — | — | US | disclosed |
| US-7994280-B2 | disulfide bond formation in solid phase peptide synthesis; starting with a cysteine that is protected in its side chain by a S-tert-butyl-sulphenyl group and which is N-terminally substituted at its N.alpha. and 3,3'-dithio-propionimide; coupling, cyclization; Eptifibatide on Sieber resin | LONZA AG (CH) | 2011-08-09 | — | — | US | disclosed |
| EP-1805203-B1 | ON-RESIN PEPTIDE CYCLIZATION | LONZA AG (CH) | 2010-01-13 | — | — | EP | disclosed |