Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | BHMT | Q93088 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788769 | 0.89 | KMT2A (0.53) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL163253 | 0.86 | TSHR (0.72) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL19838190 | 0.86 | BHMT (0.61) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL11938132 | 0.86 | KMT2A (0.50) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28696 | 0.86 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28962323 | 0.86 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL12132152 | 0.84 | BHMT (0.62) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL8257926 | 0.84 | LMNA (0.65) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL9715431 | 0.83 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL5170829 | 0.83 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153716-B2 | Dispersant for an aqueous dispersion of positively charged or chargeable solid particulates which comprises a compound having an anchoring moiety linked to a polymeric hydrophilic moiety; inkjet recording element | EASTMAN KODAK COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-8063132-B2 | Coating composition comprising boehmite particles and one or more dispersants and a method of coating a substrate using said coating composition | EASTMAN KODAK COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-20080145546-A1 | Dispersant For Reducing Viscosity Of Particulate Solids | FPC INC. | 2008-06-19 | — | — | US | disclosed |
| US-20080090012-A1 | Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity | KODAK PHILIPPINES LTD. | 2008-04-17 | — | — | US | disclosed |
| EP-1189638-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000187-A2 | PHARMACEUTICAL COMPOSITION CONTAINING SIBUTRAMINE AND A LIPASE INHIBITOR | KNOLL AKTIENGESELLSCHAFT (DE) | 2001-01-04 | — | — | WO | disclosed |
| US-4196291-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1980-04-01 | — | — | US | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090012-A1 | Aqueous boehmite particles of a hydrophilic polymer having a linked anchoring moiety which contains acid(s) and/or hydroxy(s); the polymeric moiety has a lower affinity for a boehmite surface than the anchoring moiety; mercaptosuccinic acid-modified polyacrylamide; ink jet; paper coating; gloss porousity | CD44, MPST, BHMT2 | LMNA 4534/4885KMT2A 737/4885HSD17B10 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.