Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100041 | 0.86 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28850723 | 0.82 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11938097 | 0.81 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14378449 | 0.81 | TSHR (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14378251 | 0.81 | TSHR (0.50) | TSHRTHRBTDP1ALDH1A1LMNA | |
| SCHEMBL8067583 | 0.78 | TSHR (0.49) | TSHRTHRBTDP1ALDH1A1TLR2 | |
| SCHEMBL7736289 | 0.78 | TSHR (0.77) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31207506 | 0.78 | TSHR (0.77) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29580544 | 0.78 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2912477 | 0.78 | TSHR (0.77) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160038388-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | LIVING PROOF INC (US) | 2016-02-11 | — | — | US | disclosed |
| US-20110008265-A1 | In Situ Polymerization For Hair Treatment | LIVING PROOF, INC. (US) | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110008265-A1 | In Situ Polymerization For Hair Treatment | PPOX, SUCLG1, GFER | TSHR 3539/4885THRB 3991/4885POLB 141/4885 |
| US-20160038388-A1 | HAIR CARE COMPOSITIONS AND METHODS OF TREATING HAIR USING SAME | TET1, TET2, TET3 | TSHR 3749/4885THRB 2758/4885POLB 308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.