SCHEMBL16329947

SCHEMBL16329947

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nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FGF1 P05230 9/20 0.48
FGF2 P09038 7/20 0.48
SERPINC1 P01008 1/20 0.41
HPSE Q9Y251 15/20 0.37
VEGFA P15692 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16329960 0.98 FGF1 (0.47) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL1787297 0.98 FGF1 (0.50) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL12798122 0.98 FGF1 (0.50) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14368574 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL1788586 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14368408 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL1785565 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL16329942 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL1785134 0.95 FGF1 (0.48) FGF1FGF2SERPINC1HPSEVEGFA
SCHEMBL14345974 0.93 FGF1 (0.43) FGF1FGF2SERPINC1HPSEVEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS FGF1 1447/4885FGF2 919/4885SERPINC1 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.