Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 6/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387458 | 0.93 | CA12 (0.44) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13045419 | 0.90 | CA12 (0.54) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16329974 | 0.88 | CA12 (0.52) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16299321 | 0.88 | CA12 (0.52) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16330002 | 0.88 | CA12 (0.52) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16330041 | 0.87 | TDP1 (0.57) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13045375 | 0.83 | CA12 (0.46) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16315933 | 0.82 | TDP1 (0.53) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL10085164 | 0.81 | CA12 (0.44) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL16329967 | 0.81 | TDP1 (0.51) | TDP1FOLH1PADI6CAPN1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |