Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.49 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16315933 | 0.94 | TDP1 (0.53) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL16329967 | 0.91 | TDP1 (0.51) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL16329968 | 0.90 | TDP1 (0.49) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL13045429 | 0.89 | TDP1 (0.49) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL12387577 | 0.88 | TDP1 (0.43) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL16329966 | 0.87 | CA12 (0.53) | TDP1FOLH1CAPN1PRSS1PRSS2 | |
| SCHEMBL13045423 | 0.87 | TDP1 (0.47) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL24601803 | 0.87 | FOLH1 (0.67) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL14524594 | 0.86 | TDP1 (0.43) | TDP1FOLH1CAPN1PLCD1PRSS1 | |
| SCHEMBL16350682 | 0.85 | FOLH1 (0.51) | TDP1FOLH1CAPN1PLCD1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |